NATIONAL INSTITUTES OF SCIENCE AND TECHNOLOGY - INCT of the Biomedicine of the Brazilian Semiarid
Annual Activity Report 2009
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  Home   |   Highlights  |   Thematic III  

Thematic III  -  Autonomic Nervous System and tropical neurological diseases

Goals   |   Publications  |   Books  |   Book chapters

Participants:

    Francisco de Assis A.Gondim,  Armênio A. dos Santos,  Francisco Hélio Rola,  Geanne Matos de Andrade Cunha,  Gisele R. Oliveira,  Otoni Cardoso do Vale,  and Reinaldo Barreto Oriá. 


    The third thematic proposed to develop 11 goals for which we reached during the year 2009 the following results:


    Goals:

     Study of the cycle of malnutrition and infection by Cryptosporidium parvum in the cognitive development of suckling mice

     Study of the prevalence and diagnostic of neurologic diseases in the SemiArid

     Research Autonomic deficiencies and nutritional modifications post-lesion of the spinal cord in awaken mice.

      Explore the impact of early malnutrition in Cryptosporidiosis in the cognitive development in inbred BALB-C mice line.

      Electrophysiological and semiological investigation of the Autonomic Nervous System (ANS).

      Correlation between the clinical manifestations and findings of the ANS examination.

     Follow up of studied patients to establish prognosis, taking in account possible cardiovascular manifestations and patient survival.

     Study the chronic effect of cervical CT-scan in the gastrointestinal motility of awaken mice.

     Study the nutritional modifications in the chronic phase post-cervical and upper thorax CT-scan.

     Study whether bladder distention can promote inhibition of the digestive motility in awaken rats post-CT-scan discharge.

     Establish whether the visceral distention in animals post-CT scan discharge can promote digestive motility inhibition without parallel changes in hemodynamic parameters.


    Publications


    i.  GOMES, K.N.; CÂMARA, C.C.; ARAÚJO, C.H.O.; BESSA, D.T.; LIMA, N.A.; HIRATA, F.C.C.; COSTA, S.B.C.; TEIXEIRA-SANTOS, T.J.; ROCHA, N.M.F.L.; NORÕES, L.A.; DE CASTRO-COSTA, C.M. Estudo comparativo experimental do adjuvante completo de Freund e formalina inoculados na articulação temporomandibular de ratos e consequentes alterações comportamentais por possível dor orofacial. Revista Dor, v. 10, p. 141-149, 2009.

    ii.  DE CASTRO-COSTA, C.M.; ARAÚJO, A.Q.C.; CÂMARA, C.C.; FERREIRA, A.S.; TEIXEIRA-SANTOS, T.J.; COSTA, S.B.C.; ALCÂNTARA, R.N.M.; TAYLOR, G.P. Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients. Arquivos de Neuro-Psiquiatria v. 67, p. 866-870, 2009.

    iii.   DE CASTRO-COSTA, C.M. Dor no Câncer: Tópicos Relevantes. Âmbito Hospitalar, v. 5, p. 80-83, 2009.

    iv.   DE CASTRO-COSTA, C.M. Dor Neuropática Novos Conceitos, Expressão Clínica e Desafios Terapêuticos. Prática Hospitalar v. 1, p. 109-110, 2009.

    v.   BATISTA, L.M.; BATISTA, I.M.; ALMEIDA, J.P.; CARVALHO, C.H.; COSTA, S.B.C.; DE CASTRO-COSTA, C.M. Preemptive Analgesic Effect of Lidocaine in a Chronic Neuropathic Pain Model. Arquivos de Neuro-Psiquiatria v. 67, p. 1088-1092, 2009.

    vi.   GONDIM, F.A.A.; THOMAS, F.P.; OLIVEIRA, G.R.; PIMENTEL, L.H.C.; BASTOS, B.P.R.; DE CASTRO-COSTA, C.M. On the spectrum of leprosy neuropathies: multifocal inflammatory neuropathy heralding leprosy relapse. Neuromuscular Disorders, v. 19, p. 711-713, 2009.

    vii.   ORIÁ, R.B.; DE CASTRO-COSTA, C.M.; LIMA, A.A.M.; PATRICK, P.D.; GUERRANT, R.L. Semantic fluency: a sensitive marker for cognitive impairment in children with heavy diarrhea burdens? Medical Hypotheses, v. 73, p. 682-686, 2009.

    viii.   . Castro-Silva, C.; BRUIN, V. M. S.; CUNHA, GMA; Nunes, D.M.; Medeiros, C.A.M.; BRUIN, P. F. C. Melatonin improves sleep and reduces nitrite in the exhaled breath condensate in cystic fibrosis a randomized, double-blind placebo-controlled study. Journal of Pineal Research, v. 48, p. 65-71, 2010.

    ix.   RODRIGUES, P.A.; MORAES, S.M.; SOUZA, C.M.; SILVA, A.R.; ANDRADE, GM; Silva, M.G.; RAO, Vietla Satyanaraiana; SANTOS, F.A. Gastroprotective effect of barbatusin and 3-beta-hydroxy-3-deoxibarbatusin, quinonoid diterpenes isolated from Plectranthus grandis, in ethanol-induced gastric lesions in mice. Journal of Ethnopharmacology, v. 127, p. 725-730, 2010.

    x.  PINTO, N.B.; MORAES, T.C.; CARVALHO, K.M.; SILVA, C.R.; ANDRADE, GM; BRITO, G.A.C.; PESSOA, O.D.L.; SANTOS, F.A. Topical anti-inflammatory potential of Physalin E from Physalis angulata on experimental dermatitis in mice. Phytomedicine (Stuttgart), v. 8, p. 00-01, 2010

    xi.   NOBRE JUNIOR, H.V.; OLIVEIRA, RA; MAIA, F.D.; NOGUEIRA, M.A.S.; MORAES, M.O.; BANDEIRA, M.A.M; CUNHA, GMA; VIANA, GSB. Neuroprotective Effects of chalcones from Myracrodruon urundeuva on 6-Hydroxydopamine-Induced cytotoxicity in rat mesencephalic cells. Neurochemical Research, v. 34, p. 1066-1075, 2009

    xii.  LEAL, LKAM; CANUTO, K.M.; Costa, K.C.; NOBRE JÚNIOR, HV; VASCONCELOS, S.M.M.; SILVEIRA, ER; Ferreira, M.V.; FONTENELE, J.B.; ANDRADE, GM; VIANA, GSB. Effects of Amburoside A and Isokaempferide, Polyphenols from Amburana cearensis on rodent inflammatory processes and myeloperoxidase activity in human neutrophils activity in human neutrophilis. Basic & Clinical Pharmacology & Toxicology, v. 104, p. 198-205, 2009.

    xiii.   BRUNO, R; MARQUES, T; BATISTA, T; LIMA, J; DEARRUDA, K; LIMA, P; SANTOS, N; CUNHA, GM; VITOR, H; VIANA, GSB. Pentoxifylline treatment improves neurological and neurochemical deficits in rats subjected to transient brain ischemia. Brain Research, v. 1260, p. 55-64, 2009.

    xiv.   . CANAS, P.; PORCIUNCULA, L. O.; CUNHA, GM; SILVA, C.G.; MACHADO, N.J.; OLIVEIRA, J.M.; OLIVEIRA, C. R.; CUNHA, R.A. Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway. The Journal of Neuroscience, v. 29, p. 14741-14751, 2009

    xv.   PEIXOTO Jr. AA; TELES BC; BRASIL EF; Santos AA; Oliveira GR; Ribeiro RA; Rola FH; Gondim FAA. Vincristine delays Gastric Emptying and Gastrointestinal Transit of Liquid in Awake Rats. Brazilian Journal of Medical and Biological Research, v. 42, p. 567-573, 2009.

    xvi.   Oliveira GR; Gondim FAA; Hogan E; Rola FH. Movement-Induced heart rate (HR) changes in epileptic and non-epileptic seizures. Arquivos de Neuro-Psiquiatria, v. 67, p. 789-791, 2009

    xvii.   Gondim FAA; Oliveira GR; Thomas FP. Upper gastrointestinal motility changes following spinal cord injury. Neurogastroenterology and Motility, v. 22, p. 2-6, 2010

    xviii.    Gondim FAA; Thomas FP; OLIVEIRA G; Pimentel LH; Costa CM de C. On the spectrum of leprosy neuropathies: multifocal inflammatory neuropathy heralding leprosy relapse. Neuromuscular Disorders, v. 19, p. 711-713, 2009.

    xix.    TAUNAY T; Oliveira GR; Gondim FAA. Neuroanálise: considerações sobre as bases neurobiológicas das doenças psiquiátricas. Rheumatology (Oxford), v. 2, p. 5-10, 2009



    Books

    ALVES-NETO, O. (Org.); DE CASTRO-COSTA, C.M. (Org.); SIQUEIRA, J.T.T. (Org.); TEIXEIRA, M. J. (Org.). Dor: Princípios e Prática. 1. ed. Porto Alegre-RS: Artmed Editora, 2009. v. 1. 1438 p.

    Gondim FAA; TAUNAY T; Oliveira GR; Messias EL; Costa CM de C; Rola FH; Costa HA. Neuropsicofisiologia. 1. ed. Fortaleza: Gráfica Batista, 2009. v. 1. 257 p.



    Book chapters

    DE CASTRO-COSTA, C.M.; TEIXEIRA-SANTOS, T.J.; COSTA, S.B.C. Modelos animais e laboratoriais de dor. In: NETO, O.A.; DE CASTRO-COSTA, C.M.; SIQUEIRA, J.T.T.; TEIXEIRA, M.J. (Org.). Dor: Princípios e Prática. 1 ed. Porto Alegre-RS: Artmed Editora, 2009, v. 1, p. 305-312.

    DE CASTRO-COSTA, C.M. Dor Neuropática. In: NETO, O.A.; DE CASTRO-COSTA, C.M.; SIQUEIRA, J.T.T.; TEIXEIRA, M.J. (Org.). Dor: Princípios e Prática. 1 ed. Porto Alegre-RS: Artmed Editora, 2009, v. 1, p. 495-509.

    VALL, J.; DE CASTRO-COSTA, C.M. Dor em Lesão Medular. In: NETO, O.A.; DE CASTRO-COSTA, C.M.; SIQUEIRA, J.T.T.; TEIXEIRA, M.J. (Org.). Dor - Princípios e Prática. 1 ed. Porto Alegre-RS: Artmed Editora, 2009, v. 1, p. 838-846.

    SILVA JUNIOR JTF; MONTEIRO IGL; HOLANDA CTD; Gondim FAA. Neurological Complications of Antiangiogenic Therapy. In: Malay Chatterjee; Ajay Rana; Basabi Rana. (Org.). Anti-Angiogenesis-Drug Discovery and Development. Sharjah: Bentham Science Publishers, 2010



NATIONAL INSTITUTES OF SCIENCE AND TECHNOLOGY - INCT of the Biomedicine of the Brazilian Semiarid